Compounds in Grape Skins Can Suppress Inflammation
Resveratrol, a compound found in grape and red grape skins, contain antioxidants and anti-inflammatory, so it can suppress inflammation in humans. This is the findings based on experiments by endocrinologists at the University of Buffalo, USA.
The results were published in the Journal of Clinical Endocrinology & Metabolism, July online version and will be published in the printed edition.
Husam Ghanim, PhD, assistant professor at the University of Buffalo and first author of the study, noted that resveratrol extends the life and reduce the rate of aging of yeast, roundworms, and fruit flies.
This compound is also thought to play a role in insulin resistance, a condition associated with oxidative stress (the number of free radicals in the body exceeds the body’s capacity to neutralize them).
“Because there is no data showing the effect of resveratrol against oxidative stress and inflammation in humans,” said Paresh Dandona, MD, PhD, professor of medicine at the University of Buffalo, according to sciencedaily, “we decided to determine whether these compounds reduce the level of oxidative stress and inflammation in humans.”
Nutritional supplements containing 40 milligrams of resveratrol used as an active product. Twenty participants were randomly divided into two groups each of 10 persons. One group received a supplement, while another group received a similar pill containing no active ingredients. Participants took a pill once a day for six weeks.
The results showed that resveratrol suppress free radical generation. Also suppress reactive oxygen species, unstable molecules cause oxidative stress, and release inflammatory factors into the bloodstream.