Enzyme in the brain, known as PI3 kinase , is expected to be able to control the increasing body heat that helps burn excess calories after eating foods high in fat. This was the new findings by researchers from the University of Texas (UT) Southwestern, Dallas, United States, published in the online edition of Cell Metabolism.
Increased energy expenditure, which is called the thermogenic response, burns calories even without exercising. According to Dr. Joel Elmquist, professor of internal medicine, psychiatry, and pharmacology at UT, this could help overcome obesity.
Joel Elmquist and his team experimented with a mice model in laboratory. Elmquist found that mice, which PI3 kinase activity in certain parts of the brain is reduced, are experiencing weight gain, because they can not produce thermogenic response. “Mice are more prone to obesity due to diet,” Elmquist said.
But, it remains unclear whether the findings in mice can be translated to humans because one of the tissues that mediate the thermogenic response, the brown adipose tissue, are uncommon in adult humans.
“Brown adipose tissues are found in babies. That’s why they’re so warm. But it is not clear whether this tissue has the same physiological role in adult humans,” Elmquist said.Tagged with: brain enzyme, brown adipose tissue, Burn Calories, cell metabolism, enzyme, Enzymes, Excess Calories, kinase, Obesity, thermogenic response,